General Physiology I

COURSE CURRICULUM 

1.

Course title

GENERAL PHYSIOLOGY I

2.

Code

HM-31B

3.

Study curriculum

Applied chemistry – analytical biochemistry

4.

Organizer of the curriculum (institute, department)

PMF, Institute of Chemistry

5.

Degree (BSc, MSc, PhD)

BSc

6.

Academic year/semester

II/III

7.

ECTS points

6

8.

Lecturer

Prof. Dr. Mitko Mladenov, Prof. Dr. Nikola Hadzi-Petrushev

9.

Prerequisites

General Biology

10.

Course objectives (competences):
The teaching unit contributes above all to the development of the following general and specific competencies:
- Ability to communicate, cooperation/teamwork;
- Flexible use of knowledge in practice;
- Independence, (self) criticism, (self) assessment, (self) evaluation and commitment to quality;
- Knowledge and understanding of issues related to the functioning of living organisms;
- Preparation for research in the field of physiology;
- Knowledge, understanding, orientation towards active, non-discriminatory work;
- Formation of the overall assessment of the needs of individuals, ie groups, their strengths and weaknesses, respecting the factors of the environment (physical, social, cultural), with appropriate procedures.

11.

Course content:
Importance of physiology as a biological science; Functional organization and control of the "internal environment"; Transport of ions and molecules across the cell membrane; Membrane potentials and action potentials; Contraction of skeletal muscles; Neuromuscular transmission and coupling of excitation and contraction; Contraction and excitation of smooth muscles; Organization of the nervous system, basic functions of synapses, neurotransmitters; Sensory receptors, neural pathways for information processing; Somatic sensations - general organization, tactile and positional senses; Pain and thermal sensations; Optics of vision; Receptor and neural function of the retina; Central neurophysiology of vision; Sense of hearing; Chemical senses – taste and smell; Vestibular sensations and balance maintenance; Motor functions of the spinal cord, spinal reflexes; Control of motor function by the cortex and brainstem; Cerebellum, basal ganglia and gross motor control; Cerebral cortex, intellectual functions of the brain, learning and memory; Limbic system and hypothalamus; States of brain activity; Autonomic nervous system and adrenal medulla; Blood flow through the brain, cerebrospinal fluid and metabolism in the brain; Introduction to the endocrine system; Pituitary hormones and their control by the hypothalamus; Thyroid hormones; Adrenal cortex hormones; Insulin and glucagon; Parathyroid hormone, calcitonin, calcium and phosphate metabolism; Physiology of the reproductive system.

12.

Teaching methods: Lectures, reading scientific literature, projects.

13.

Total available time

180 hours

14.

Time distribution

3+2 hours per week (lectures, experimental work, independent work, projects, homework)

15.

Teaching methods distribution

15.1.

Teaching - lectures

45 hours

15.2.

Practicals (laboratory, problem solving), seminars, team work

30 hours

16.

Other activities

16.1.

Projects

15 hours

16.2.

Independent work

10 hours

16.3.

Homework

80 hours

17.

Grading methods

17.1.

Tests

60 points

17.2.

Seminars/projects (written/oral presentation)

25 points 

17.3.

Activity

15 points

18.

Grading scale (points/mark)

< 50 points

5 (five) (F)

51 to 60 points

6 (six) (E)

61 to 70 points

7 (seven) (D)

71 to 80 points

8 (eight) (C)

81 to 90 points

9 (nine) (B)

91 to 100 points

10 (ten) (A)

19.

Criteria for taking the final exam

Attendance at lectures and finished experimental work

20.

Course language

Macedonian

21.

Teaching quality control

Evaluation, self evaluation

22.

Literature

22.1.

Compulsory

No.

Author

Title

Publisher

Year

1.

Guyton A. K., Hall G. E.

Medical Physiology

Academic press

2012

2.

3.

22.2.

Additional

No.

Author

Title

Publisher

Year

1.

Linda Costanzo

Physiology, 7th ed.

Elsevier

2021

2.

Волтер Ф. Борон В. Ф., Булпап Е. Л.

Медицинска физиологија

МОН на Р. Македонија

2011

3.

4.