Theoretical Organic Chemistry

COURSE CURRICULUM

1.

Course title

THEORETICAL ORGANIC CHEMISTRY

2.

Code

HM-555

3.

Study curriculum

All chemistry study programs

4.

Organizer of the curriculum (institute, department)

Faculty of Natural Sciences and Mathematics,
Institute of Chemistry

5.

Degree (BSc, MSc, PhD)

BSc

6.

Academic year/semester

IV/VII

7.

ECTS points

4

8.

Lecturer

Ljupco Pejov, Full professor

9.

Prerequisites

Organic chemistry I

10.

Course objectives (competences):
The aim of this subject is for the student to solidify their understanding of organic chemistry. The material develops the theoretical foundations of modern organic chemistry, which is why in the course, the student will become acquainted in detail with the theoretical aspects of organic reactions and the mechanisms by which they are carried out.

11.

Course content:
Chemical bonds, representation of structural formulas, atomic orbitals, hybridization. Huckel's method, semi-empirical methods. Method of valence bond resonance. Molecular mechanics calculations method. Graph theory in chemistry. Theories of acids and bases (Arrhenius-Ostwald, solvent theory, proton theory, electronic theory). Classification of organic reactions (types, reaction mechanism, reaction kinetics). Electronic effects (inductive effect, mesomeric and electromeric effect, hyperconjugation, electronic influences). Determination of electrophilic and nucleophilic character of reactions, kinetically and thermodynamically controlled reactions, assessment of chemical reactivity. Theoretical methods for modeling biologically relevant systems.

12.

Teaching methods: lectures, auditorium exercises

13.

Total available time

120

14.

Time distribution

2+1 hours per week (lectures 30 hours, exercises 15 hours)

15.

Teaching methods distribution

15.1.

Teaching - lectures

30

15.2.

Practicals (laboratory, problem solving), seminars, team work

15

16.

Other activities

16.1.

Projects

15

16.2.

Independent work

15

16.3.

Homework

45

17.

Grading methods

17.1.

Tests

70

17.2.

Seminars/projects (written/oral presentation)

10

17.3.

Activity

20

18.

Grading scale (points/mark)

< 50 points

5 (five) (F)

51 to 60 points

6 (six) (E)

61 to 70 points

7 (seven) (D)

71 to 80 points

8 (eight) (C)

81 to 90 points

9 (nine) (B)

91 to 100 points

10 (ten) (A)

19.

Criteria for taking the final exam

Attendance at lectures and completed exercises

20.

Course language

Macedonian

21.

Teaching quality control

anonymous survey, conversation with students

22.

Literature

22.1.

Compulsory

No.

Author

Title

Publisher

Year

1.

 Bogdan Bogdanov, Full proffesor

ТЕОРЕТСКА ОРГАНСКА ХЕМИЈА, ISBN 9989-785-41-4

Skopje

2002

2.

Carey, F. A.; Sundberg, R. J.

Advanced organic chemistry; 4th ed

Kluwer Academic/ Plenum Pub: New York

2000

3.

Bogdan Bogdanov, Full proffesor

ПРАКТИКУМ ПО ТЕОРЕТСКА ОРГАНСКА ХЕМИЈА

Skopje

2002

22.2.

Additional

No.

Author

Title

Publisher

Year

1.

March, J. Wiley: New York, 1992.

Advanced organic chemistry: reactions, mechanisms, and structure; 4th ed

Wiley: New York

1992