Chemistry of Heterocyclic Compounds

COURSE CURRICULUM

1.

Course title

CHEMISTRY OF HETEROCYCLIC COMPOUNDS

2.

Code

HM-652

3.

Study curriculum

All chemistry study programs

4.

Organizer of the curriculum (institute, department)

Faculty of Natural Sciences and Mathematics,
Institute of Chemistry

5.

Degree (BSc, MSc, PhD)

BSc

6.

Academic year/semester

III/VI

7.

ECTS points

4

8.

Lecturer

Emil Popovski, Full professor

9.

Prerequisites

Organic chemistry II

10.

Course objectives (competences):
The aim of this course is to acquaint students with common cyclic compounds that contain one or two heteroatoms in their structure. Students will learn to recognize basic structures, to name them, and to link them with the chemical and physical characteristics of the compounds in whose structure they are incorporated.

11.

Course content:
Introduction to heterocyclic compounds. Reactions for ring formation. Nomenclature of heterocyclic compounds. Three-membered heterocyclic compounds with one heteroatom (aziridines, epoxides, episulfides). Four-membered heterocyclic compounds with one heteroatom (azetidines, oxetanes, thiethanes). Five-membered heterocyclic compounds with one heteroatom (pyrrole and derivatives, furan and derivatives, thiophene and derivatives). Six-membered heterocyclic compounds with one heteroatom (pyridine and derivatives, fused pyridines, pyrylium cation, pyranones, chromenones). Six-membered heterocyclic compounds with two heteroatoms (pyridazines, pyrimidines, pyrazines, quinoline, oxazines, thiazines, piperazines, dioxanes, morpholine).

12.

Teaching methods: lectures and laboratory exercises

13.

Total available time

120

14.

Time distribution

2+1 hours per week (lectures 30 hours, laboratory exercises 15 hours)

15.

Teaching methods distribution

15.1.

Teaching - lectures

30

15.2.

Practicals (laboratory, problem solving), seminars, team work

15

16.

Other activities

16.1.

Projects

15

16.2.

Independent work

20

16.3.

Homework

40

17.

Grading methods

17.1.

Tests (quizzes and/or written exam/oral examination)

70

17.2.

Individual work/project (presentation: written/oral)

10

17.3.

Activity, participation, results from exercises

20

18.

Grading scale (points/mark)

< 50 points

5 (five) (F)

51 to 60 points

6 (six) (E)

61 to 70 points

7 (seven) (D)

71 to 80 points

8 (eight) (C)

81 to 90 points

9 (nine) (B)

91 to 100 points

10 (ten) (A)

19.

Criteria for taking the final exam

Attendance at lectures and completed exercises

20.

Course language

Macedonian

21.

Teaching quality control

Anonymous survey conducted among the students

22.

Literature

22.1.

Compulsory

No.

Author

Title

Publisher

Year

1.

Emil Popovski

Хемија на хетероциклични соединенија

Internal script

2.

Bell C. E.; Taber D. F.; Clark A. K.

ORGANIC CHEMISTRY LABORA­TORY WITH QUALITATIVE ANALYSIS: STANDARD AND MICROSCALE, 3^rd edition

2001

3.

Z. Zdravkovski, K. Stojanoski

ОСНОВИ НА ОРГАНСКАТА НОМЕНКЛАТУРА: СПОРЕД ПРАВИЛАТА НА IUPAC

Faculty of Natural Sciences and Mathematics, Skopje

2003