Instrumental Analytical Methods

COURSE CURRICULUM

1.

Course title

INSTRUMENTAL ANALYTICAL METHODS

2.

Code

HM-502

3.

Study curriculum

All study programs in chemistry

4.

Organizer of the curriculum (institute, department)

Institute of Chemistry, Faculty of Natural Sciences and Mathematics

5.

Degree (BSc, MSc, PhD)

BSc

6.

Academic year/semester

III/V

7.

ECTS points

8

8.

Lecturer

Prof. Dr. Marina Stefova

9.

Prerequisites

Analytical chemistry I

10.

Course objectives (competences):
Through the lectures and exercises students should understand and gain knowledge of the basic principles of instrumental analytical techniques, obtain basic laboratory experience and ability to make use of analytical instrumentation and data analysis which will be beneficial for their future career in chemical laboratories.

11.

Course content:
–    Introduction: analytics, analytical process, sample preparation for analysis (classical and modern techniques), classification of instrumental analytical methods;
–    Optical methods, principle, instruments and application: absorption, emission, fluorescence; molecular spectroscopy: UV-Vis, IR, fluorescence, NMR, atomic absorption and emission spectroscopy, other methods: turbidimetry, nephelometry, refractometry, polarimetry;
–    Mass spectrometry: principle and application, types of mass spectrometers, types of ionization techniques, mass spectra analysis;
–    Electroanalytical methods, principles and application: conductometry, potentiometry (reference and indicator electrodes, membrane electrodes), coulometry (basic principle and application), electrogravimetry (at constant applied potential and at constant potential of the working electrode), voltammetry (fundamentals of polarography and hydrodynamic voltammetry);
–    Separation methods: basics of a chromatographic process, gas chromatography (principle, columns, instruments, application), high-performance liquid chromatography (principle, types, columns, application), capillary electrophoresis (principle, electroosmotic flow, instruments, application), capillary electrochromatography and supercritical fluid chromatography (basic principles)

12.

Teaching methods: lectures, laboratory classes, problem solving, projects, homework

13.

Total available time

240

14.

Time distribution

4+1+3 hours weekly (lectures: 60 hours;
problem solving: 15 hours; laboratory classes: 45 hours)

15.

Teaching methods distribution

15.1.

Teaching - lectures

60 hours

15.2.

Practicals (laboratory, problem solving), seminars, team work

60 hours

16.

Other activities

16.1.

Projects

15 hours

16.2.

Independent work

15 hours

16.3.

Homework

90 hours

17.

Grading methods

17.1.

Tests

80 points

17.2.

Seminars/projects (written/oral presentation)

/ points

17.3.

Activity

 20 points

18.

Grading scale (points/mark)

< 50 points

5 (five) (F)

51 to 60 points

6 (six) (E)

61 to 70 points

7 (seven) (D)

71 to 80 points

8 (eight) (C)

81 to 90 points

9 (nine) (B)

91 to 100 points

10 (ten) (A)

19.

Criteria for taking the final exam

Attendance at lectures and completed lab exercises

20.

Course language

Macedonian, English

21.

Teaching quality control

Anonymous surveys, questionnaires

22.

Literature

22.1.

Compulsory

No.

Author

Title

Publisher

Year

1.

D.A. Skoog, D.M. West, F.J. Holler, S.R. Crouch

Analytical Chemistry: An Introduction (in Macedonian)

Prosvetno delo, Skopje

2009

2.

D. Harvey

Modern Analytical Chemistry
(in Macedonian)

Prosvetno delo, Skopje

2009

3.

Jasmina Petreska Stanoeva, Miha Bukleski, Marina Stefova

Numerical problems in analytical chemistry and instrumental analysis (in Macedonian)

UKIM

2020

22.2.

Additional

No.

Author

Title

Publisher

Year

1.

D.A. Skoog, D.M. West, F.J. Hooler

Fundamentals of Analytical Chemistry, Seventh Ed.

Saunders College Publishing

1996

2.

D.A. Skoog, F.J. Hooler,  T.A. Nieman

Principles of Instrumental Analysis,Fifth ed.

Saunders College Publishing

1998